The Role of Bronchoalveolar Lavage in Diagnosing Nonopportunistic Bacterial Pneumonia (13)

In: Pulmonary function

5 May 2013

The Role of Bronchoalveolar Lavage in Diagnosing Nonopportunistic Bacterial Pneumonia (13)In a baboon model of respiratory failure, the results of quantitative cultures of BAL and PSB were compared with the histologic and bacteriologic findings of open-lung biopsy. Six ventilated animals not receiving antibiotics had, on histologic examination, moderate to severe pneumonia and a polymicrobial growth on culture; BAL recovered 74 percent of all species present in the lung tissue compared with 41 percent by PSB and 56 percent by ‘needle aspirate. Bacterial growth in the BAL, expressed as bacterial index (sum of all the logarithmic concentrations of individual organisms), was linearly related to tissue values.

Tissue cultures had a mean growth of 2.8 species at 103 cfu/g and 1.4 species at 104 cfu/g. In animals receiving antibiotics, absence of growth was frequently found despite histologic evidence of pneumonia. The investigators concluded that BAL specimens, by sampling a larger area of lung parenchyma, provided (in animals not receiving antibiotics) the most accurate window on lung microbiology, both quantitatively and qualitatively. Buy Advair Diskus Online
Three investigators have evaluated the role of BAL in diagnosing nosocomial bacterial pneumonia in patients receiving mechanical ventilation. Torres et al have compared the diagnostic yield of PSB and BAL in 25 patients with VAP recently (^12 h) placed on antibiotic therapy.


About this blog

Blog invites submissions of review articles, reports on clinical techniques, case reports, conference summaries, and articles of opinion pertinent to the control of pain and anxiety in dentistry.

Photostream

Future-Farmers-Of-America
Massive NIH Grant to Study Benefits of SMT for Back Pain https://t.co/aTw5IPC02k
Federal agencies partner for military and veteran pain management research https://t.co/3DnUOgQ1Lt https://t.co/zrodBLjyKd
Artemisia - mugwort, wormwood, and sagebrush belonging to the daisy family Asteraceae
Artemisia - mugwort, wormwood, and sagebrush belonging to the daisy family Asteraceae
Bunch of juniper berries on a green branch in autumn
Bunch of juniper berries on a green branch in autumn
Bunch of juniper berries on a green branch in autumn
Stethoscope and keyboard macro concept

Tags