The frequency of vitamin D deficiency in adults with Crohn’s disease: Seasonal variation of 25-OHD levels

In: Crohn's disease

3 Aug 2012

Finally, only two of the 19 patients with low serum 25-OHD had elevated serum PTH levels above the upper limit of normal (greater than 6.8 pmol/L) at baseline. Both patients reported being smokers and one of these patients had a BMI of 17.6 kg/m2. In both cases, serum alkaline phosphatase levels were within normal range (30 to 130 IU/L).

Table 4 shows the number of patients with deficient and normal 25-OHD levels, relative to the seasonal time of measurement (ie, winter, October to March, and summer, April to September). Sixteen (84.2%) of the 19 patients with deficient 25-OHD levels were identified during the winter.

 

When the frequency of 25-OHD deficiency in patients during summer and winter periods was compared, patients in the winter period exhibited a significantly higher frequency of vitamin D deficiency than did patients in the summer period (11.9% versus 2.8%, respectively, P=0.02). You have a great opportunity to find cialis 200mg buy here to feel one lucky customer.

TABLE 4 The number of patients with deficient and normal 25-hydroxyvitamin D3 (25-OHD) levels, relative to the seasonal time of measurement (ie, winter, October to March and summer, April to September)

Summer Winter
Patient group n (%) n (%)
Normal serum 25-OHD levels (n=218) 105 (47.1) 118 (52.9)
Deficient serum 25-OHD levels (n=19) 3 (15.8) 16 (84.2)
Percentage 25-OHD deficiency (2.8) (11.9)*

25-OHD deficiency is defined as a serum 25-OHD concentration below

25 nmol/L. *P=0.02 relative to summer months


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