The frequency of vitamin D deficiency in adults with Crohn’s disease: Determinants of 25-OHD deficiency

In: Crohn's disease

2 Aug 2012

Biochemical characteristics

Pearson correlation was carried out between serum 25-OHD and clinical characteristics in the Crohn’s disease population. Carotene and RBC folate both positively correlated with serum 25-OHD (r=0.250 and r=0.349, respectively, P<0.05) in the male population. In addition to the positive correlation with carotene and RBC folate (0.292, and 0.184, respectively, P<0.05) in the female Crohn’s disease population, smoking negatively correlated with serum 25-OHD (r=—0.258, P<0.05), and serum creatinine and iron positively correlated with serum 25-OHD (r=0.186, 0.226, respectively, P<0.05). Safe online shopping for drugs: *cheap viagra pills to make your drugs cheaper.

When forward regression analysis was performed, only RBC folate predicted serum 25-OHD (r=0.325, P<0.05) in the male Crohn’s disease population. In the female Crohn’s disease population, smoking, RBC folate and serum iron predicted serum 25-OHD (r=0.418, P<0.05). PTH was excluded from this analysis because of its known relationship to vitamin D.

When serum levels of 25-OHD were compared in smokers and nonsmokers with Crohn’s disease, 25-OHD was significantly lower in smokers (49.4±21.6 versus 58.3±23.3, respectively, P<0.005).


About this blog

Blog invites submissions of review articles, reports on clinical techniques, case reports, conference summaries, and articles of opinion pertinent to the control of pain and anxiety in dentistry.