Posts Tagged ‘Nitrous oxide

Inhalation Sedation for Outpatient

This pilot study attempted to determine whether sevoflurane as a sole agent could be used as a deep sedative agent for minor surgical procedures in healthy young adults. Additionally, the quality of the sedation and the vital signs changes were compared […]

Twenty-four patients were initially enrolled in the study. One patient, a 25-year-old, 80-kg woman, developed nausea after 2 minutes of sevoflurane administration at a final vaporizer setting of 0.5%. After 3 to 4 minutes, her feeling of nausea subsided. The patient was withdrawn from the study. A conscious sedation was then planned and 10 mg of diazepam was slowly titrated. Shortly thereafter, the patient reported that she felt more relaxed […]

After approval from the Ohio State University Human Subjects Review Committee, 24 patients (17 women and 7 men) were enrolled in the study. All patients were American Society of Anesthesiologists (ASA) Physical Status I or II and between 18 and 40 years of age. Patients who were currently using benzodiazepines, antidepressants, or long-term analgesics were excluded from the study. Likewise, patients with a recent history of renal disease or documented […]

Inhalation Sedation

The use of the conscious inhalation sedative nitrous oxide has a long history of success and safety in the dental office provided that supplemental oxygen is administered. Nitrous oxide-oxygen inhalation sedation has a rapid onset and recovery, provides varying degrees of analgesia, and has minimal respiratory, cardiovascular, and other adverse effects. This is likely the […]

Respiratory system

Our results demonstrate that sevoflurane and isoflurane but not enflurane decrease Spo2 in infants receiving 67% nitrous oxide and oxygen. A preliminary study indicated that this phenomenon was not commonly observed with low concentrations of sevoflurane or isoflurane or in patients over 3 years of […]

There were no significant differences among the three experimental groups with regard to age, body weight, or height (Table 1). The mean values (and standard deviations) for Spo2, heart rate, blood pressures, Petco2, and body temperature are listed in Table 2 by group and stage. In the sevoflurane and isoflurane groups, the mean Spo2 in stage 2 was significantly higher than in stages 1 and 3 (paired t test) but […]


Seventy infants under 2 years of age without any respiratory or cardiovascular dysfunction were studied during general anesthesia for repair of a cleft lip or palate. After informed written consent was obtained from the parents, subjects were allocated randomly into 3 groups (sevoflurane group, n = 24; enflurane group, n = 26; isoflurane group, n = 20). Premedication consisted of oral diazepam (0.1 mgAg) and intramuscular atropine sulfate (0.01 […]

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Blog invites submissions of review articles, reports on clinical techniques, case reports, conference summaries, and articles of opinion pertinent to the control of pain and anxiety in dentistry.