Posts Tagged ‘Ketamine

Analgesia Sedation DISCUSSION

The intranasal route of administration shows promise. The intranasal route is one of the most permeable and highly vascularized sites for drug administration, ensuring rapid absorption into the systemic circulation and onset of therapeutic action. In general, it has been potentially explored […]

Patients in the 2 groups were similar with respect to age, height, weight, gender distribution, and length of surgery, and the number of teeth removed (Table 1). There were no significant differences (P = .05) in the physiological parameters, namely blood pressures (systolic, diastolic, mean arterial), heart rates, respiratory rates, and oxygen saturation between the 2 groups at the various time intervals measured (Table 2). With regard to the preoperative […]

The University Ethics Committee approved the study, and the parents signed written consent forms. Fifty healthy ASA status 1 children, free of any nasopharyngeal or respiratory problems, aged 5-7 years, weighing 15-20 kg, and having 6 or more teeth extracted, were eligible for participation in the study. Exclusion criteria were as follows: the use of analgesics or central nervous system depressants over the previous 24 hours; the use of anticoagulants; […]

Analgesia Sedation

An increasing number of children are undergoing day-case surgery. Children from 3 to 5 years of age may experience significant emotional upset as a result of hospitalization, fear of separation from parents, and unfamiliar surroundings. Children in this age group may not be fully aware of the necessity of their surgical procedure. They are fearful of injections and cannot be easily reassured with an explanation. The primary clinical […]


Obesity, defined as a body mass index (BMI) greater than 30 kg/m2 of body surface area, is rampant in the United States. It is estimated that 4% of middle-aged men and 2% of middle-aged women have clinically significant obstructive sleep apnea (OSA) and that obesity is an independent causative risk factor in 60 to 90% of them. OSA is defined as a cessation of airflow for more than […]


The encouraging combination of these 2 relatively short-acting agents with similar pharmacokinetics and complimentary pharmacological properties, which lacks ketamine’s adverse reactions, has been clearly substantiated.

Midazolam is the benzodiazepine of choice when combined with ketamine in terms of physiological homeostasis and recovery time.

Oxygen saturation levels remained high at approximately 99%. Respiration rate did not alter significantly from baseline levels throughout the study period.

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Blog invites submissions of review articles, reports on clinical techniques, case reports, conference summaries, and articles of opinion pertinent to the control of pain and anxiety in dentistry.