That is, on average, a patient who exercises to angina with three-vessel CAD is likely to have a greater amount of ischemic myocardium than a patient with two-vessel disease who also exercises to angina. Moreover, the same reasoning suggests that a larger sample population of normal subjects may have allowed a statistically significant difference in exercise ST decrease among normal subjects and coronary patient groups 1 and 4.
One difference between the results of this study and those of our previous exercise BSPM study of 14 patients with isolated left anterior […]
Previous quantitative exercise BSPM studies in patients with CAD are scarce.’ One study of 100 patients suggested a positive correlation between the number of obstructed coronary arteries and both the severity of exercise ST depression at 80 ms after QRS offset and the anterior torso area over which it occurred. In another study of 27 patients the authors considered the size of the torso area of ST depression, 60 ms […]
Certainly, the epidemiologic data from two recent studies of large patient populations have shown that the degree of exercise ST deviation, as measured from 12- […]
There were three major findings in this study. First, exercise BSPM provided quantitative discrimination among individual patients and patient groups with single- and multiple-vessel CAD. On average, patients with underlying multiple-vessel CAD and angina-limited exercise had significantly greater exercise ST integral decrease than patients with single-vessel CAD and angina. The CAD patients who fatigued during exercise had the same degree of ST change as single-vessel disease CAD patients who achieved […]
Quantitative Coronary Angiography
The modified Gensini scores of all CAD patients are displayed in Table 1. Groups 2 and 3 had similar mean scores (68 ± 30, group 2 vs 56 ± […]
As a discriminating variable, sum ST decrease ^ — 4,000 jjlV#s, cessation minus rest, appeared to provide the best criterion for prediction of single-vs multiple-vessel CAD in patients who achieved angina (Table 2). Retrospective application of this criterion to CAD groups 1 to 3 yielded a sensitivity of 85 percent, a specificity of 70 percent, a positive predictive value of 65 percent and a negative predictive value of 90 percent […]
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