This pilot study attempted to determine whether sevoflurane as a sole agent could be used as a deep sedative agent for minor surgical procedures in healthy young adults. Additionally, the quality of the sedation and the vital signs changes were compared with a common intravenous technique used by most dentist anesthesiologists and in many hospital [...]

Twenty-four patients were initially enrolled in the study. One patient, a 25-year-old, 80-kg woman, developed nausea after 2 minutes of sevoflurane administration at a final vaporizer setting of 0.5%. After 3 to 4 minutes, her feeling of nausea subsided. The patient was withdrawn from the study. A conscious sedation was then planned and 10 mg [...]

After approval from the Ohio State University Human Subjects Review Committee, 24 patients (17 women and 7 men) were enrolled in the study. All patients were American Society of Anesthesiologists (ASA) Physical Status I or II and between 18 and 40 years of age. Patients who were currently using benzodiazepines, antidepressants, or long-term analgesics were [...]

The use of the conscious inhalation sedative nitrous oxide has a long history of success and safety in the dental office provided that supplemental oxygen is administered. Nitrous oxide-oxygen inhalation sedation has a rapid onset and recovery, provides varying degrees of analgesia, and has minimal respiratory, cardiovascular, and other adverse effects. This is likely the [...]