DISCUSSION
This study confirms the sensitivity of BIS monitoring for sevoflurane at the highest concentration studied, 0.8% inspired sevoflurane with average BIS depression from the 90s into the 80s. Overall, BIS functioned without any noticeable problems in a dental setting without a procedure being performed. At light levels of sedation, EMG activity, including eye motion, did [...]

Demographic characteristics of the 22 subjects appear in Table 2. The ratio of males to females was 12 to 10, with a mean age of 29 ± 7 years and average weight of 159 ± 36 lb. Data for vital signs appear in Table 3, expressed as means ± standard errors for the combined control [...]

With the approval of The Ohio State University IRB Human Subjects Committee, 22 healthy volunteer dental students, both male and female, were recruited in pairs to participate in a single-blinded clinical protocol. A power analysis was performed on data from previous similar studies and indicated that an N (least significantnumber) greater than 15 should provide [...]

This study sought to characterize the effects of 3070% nitrous oxide and 0.2-0.8% sevoflurane conscious sedation on quantitative electroencephalographic (EEG) readings as measured by the bispectral index (BIS). BIS is a processed parameter (algorithm) made available in 1997 by Aspect Medical Systems (Newton, Mass). As depicted in Figure 1, it is specifically designed to correlate [...]