The lack of significant correlation between PEEP and the IR, and the fact that in three patients, despite the change in PEEP (although small) and an unchanged EVLW, the IR remained within a 10% change, prove the independency of the IR in relation to the PEEP. Second, pleural effusion interfered with transthoracic impedance measurements of EVLW. Because the presence of EVLW by EIT is determined by the gas inflation differences, […]
Our data show that EIT, by using an IR that is based on ventilation-induced impedance changes in the anterior and the posterior parts of the lung, is a […]
Two reproducible measurements could not be obtained in two patients because of the disturbing influences of subcutaneous emphysema and edema on EIT measurements, and these were excluded from the analysis. The calculated CV was 4.1%, whereas the RC was 92%. A significant correlation of 0.91 (p < 0.001) between the analyses by both observers was found.
To assess the diagnostic performance of EIT in the ROC curve, an EVLW […]
Assessment of EVLW
Twenty-nine measurements in 14 patients could be performed. In two patients, no second day follow-up measurement could be performed due to […]
Two independent observers blinded for the EVLW measurements by the TDD analyzed the EIT measurements. Interobserver variation was studied by calculating Pearson’s correlation coefficient. Receiver operator characteristic (ROC) analysis was used to assess the optimal cutoff level of the IR to diagnose an increased amount of EVLW (> 10 mL/kg). The ROC curve shows the calculated sensitivity and specificity for a test over a range of cutoff points and can […]
TDD: In this study, TDD assessment of the amount of EVLW was performed using the COLD System (Pulsion Medical Systems; Munich, Germany). The principle is based on […]
In ARDS, lung density increases from the ventral to the dorsal lung regions in the supine position and an increased amount of EVLW causes compression atelectasis in the posterior part. Because EIT can visualize regional ventilation, we hypothesized that differences in the ventilation-induced impedance changes occurring between the anterior part and posterior part of the lungs may provide information about the EVLW content.
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