Posts Tagged ‘cough

chronic respiratory diseasesThis is the first study to compare the impact of cough on HRQoL across a range of common chronic respiratory diseases using validated cough-specific quality of life questionnaires. We have demonstrated that the magnitude of cough-specific HRQoL impairment is similar among all respiratory disease groups studied and is greatest among female patients. Generic measures of HRQoL in COPD […]

gastroesophageal refluxTable 1 contains baseline characteristics of the 147 patients recruited to the four groups as well as test statistics for comparisons of these characteristics between the groups. Diagnostic categories in the chronic cough group were as follows: gastroesophageal reflux, 35%; asthma, 21%; idiopathic cough, 12%; postnasal drip, 7%; postviral, 6%; eosinophilic bronchitis, 6%; and other, 13% (eg, angiotensin-converting enzyme inhibitor-related […]

Chronic coughChronic cough is not a trivial symptom and is associated with significant impairment in health status. Health-related quality of life (HRQoL) questionnaires provide one means of measuring health status and are increasingly used in clinical studies, Two cough-specific quality of life questionnaires have been developed and validated: the Leicester Cough Questionnaire (LCQ), and the Cough Quality of Life Questionnaire (CQLQ). […]

The study groups were relatively small in most of the reports. Only four studies had more than 20 subjects who completed the protocol (Table 1). This raises concerns that a beta error may have masked a beneficial effect of medical antireflux therapy. The average change in FEV1 in these studies was less than 5%, with an SD of approxi mately 30%. The required sample size, with an alpha of 0.05 […]

Does Medical Antireflux Therapy Improve Asthma in Asthmatics With Gastroesophageal Reflux: Alternative HypothesesThese studies may have been too short to allow the complete benefit from antireflux therapy to become apparent. One surgical series presented 5-year follow-up data indicating an improvement in lung function. One half of the patients in […]

Because there have been relatively few studies using each antireflux medication, all of the English-language, peer-reviewed, placebo-controlled studies of the effects of antireflux medication on asthma were combined for analysis. The inclusion of studies using the different antireflux regimens is justified by the similarity of their outcomes. The combined data show that the majority of patients experienced an improvement in asthma symptoms and their asthma medication requirements decreased, even though […]

Does Medical Antireflux Therapy Improve Asthma in Asthmatics With Gastroesophageal Reflux: AnalysisThe subjects were divided into treatment responders and nonresponders. Improvement was defined by the presence of at least one of the following: asthma symptom score reduction of more than 20%, PEF improvement by more than 20%, total number of […]

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Blog invites submissions of review articles, reports on clinical techniques, case reports, conference summaries, and articles of opinion pertinent to the control of pain and anxiety in dentistry.