In: Asthma26 Jan 2013
The coefficient of variation of the PEFR was calculated over the 13-hour measurement period on the control day in the 81 asthmatic patients who cycled and was compared with the PEFR variability in the groups of study 1 and 2. To assess whether a late fall in PEFR ^20 percent was more frequent on the exercise day than on the control day, McNemars test for paired dichotomic observations was used. The magnitude of the early and the late fall in PEFR on the exercise day was compared by a two-tailed paired t test. In patients in whom no PEFR measurements were missing, the difference between the values of the early and the late fall in PEFR on the exercise and the control day was analyzed by repeated measurements analysis of variance. An early fall was defined herein as a >20 percent fall from baseline PEFR within 1 hour after EC. buy asthma inhaler
The mean coefficient of variation in 21 patients of the PEFR on both control days was 4.6 ±2.9 percent. It was slightly larger on the first day (5.1 ± 3.3 percent) than on the second (4.0 ±2.6 percent). When these coefficients of variation of the PEFR on the first and second study day were compared by a two-tailed paired t test, the difference was not statistically significant (p>0.15).
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