Pneumothorax with Pneumocystis carinii Pneumonia in AIDS (5)

In: Pulmonary function

15 Jun 2013

Pneumothorax with Pneumocystis carinii Pneumonia in AIDS (5)Discussion
This retrospective review of all AIDS patients seen in the three largest teaching hospitals in Denver from May 1982 through April 1987 demonstrates an increased incidence of pneumothorax in patients with PCP (9.0 percent). Not a single case of pneumothorax was observed in AIDS patients without PCP All of the pneumothoraces resolved, most with conservative managment.
In the 50 years following the original description of P carinii by Delano and Delano, the organism was considered to be an infrequent cause of human disease.- The rapid proliferation of immunosuppressive agents, organ transplantations, and the recent AIDS epidemic have dramatically increased the incidence of pneumonia caused by this organism. Currently, P carinii pneumonia is the most common opportunistic infection in patients with AIDS, accounting for a large proportion of overall morbidity and mortality in these patients. The recent increase in the number of patients with documented PCP has allowed for the greater observation of infrequent complications of this pneumonia. Previous reviews of P carinu-associated disease mentioned the presence of cysts, blebs, pneumatoceles, cavities, or pneumothoraces only rarely or not at all in association with PCP Recently there have been several articles noting the association of pneumothorax with PCP.

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