Enfuvirtide: PHARMACOKINETICS
In: Drug
9 Jun 2010Enfuvirtide is a synthetic peptide and is thus not bioavailable orally. Following a twice-daily subcutaneous injection of 30 to 90 mg, its bioavailability is approximately 84.3%. Comparable absorption of the 90-mg dose has been reported in different injection sites of the abdomen, thigh, and arm.
Enfuvirtide
In: Drug
8 Jun 2010
Acquired immunodeficiency syndrome (AIDS) continues to pose an overwhelming burden on public health. According to estimates from the Joint United Nations Programme on HIV.
Computers and Patient Safety
In: Main
7 Jun 2010
Computerized Physician Order Entry (CPOE)
A wanted to thank you for publishing the editorial written by Karl Matuszewski (”The Emperor’s New Clothes?”, September 2003). I strongly agree with his comments.
The January 2003 First Consulting Group report estimates an average cost of $12 million for the implementation of CPOE per hospital, with an annual maintenance cost of 12% of the initial investment. According to this report, an estimated 5% of American hospitals currently use CPOE. One of the claimed benefits of CPOE is a reduction of prescribing and medication errors, although there are currently few scientific data available to substantiate this. As Dr. Matuszewski notes, not using CPOE is considered almost criminal by some self-appointed quality experts. This belief in CPOE is pervasive among health care workers.
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- Tags: Patient Safety
The Hubbub About RxHub
In: Main
6 Jun 2010Do physicians in your organization complain about the prescription-writing process with all of its inherent “handoffs” and potential problems? Do patients in your organization voice their concerns about filling prescriptions in a convenient and safe manner? Does your pharmacy always search for ways to improve productivity in the prescription delivery process? Does your leadership look for ways to reduce administrative time and associated costs?
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- Tags: Hubbub
Guardian of the Night Pharmacy: part 2
In: Health
5 Jun 2010Unfortunately, the expense of such sophisticated systems can outstrip the constrained budgets of small hospitals. Under
The views expressed in this article are those of the authors and do not necessarily reflect those of P&T.
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- Tags: Guardian, Night Pharmacy
Guardian of the Night Pharmacy
In: Health
4 Jun 2010
Horus was the hawk-headed god of ancient Egypt who still stands guard over temples and pyramids. Legend has it that during a series of violent family upheavals, Horus lost both of his eyes and was rendered unable to protect his family. However, his appeals to the gods for release from his blindness were answered and his eyesight was restored and fortified. His right eye was replaced with the sun, and the moon became his left eye. With this celestial combination, Horus has endured in stone and in legend over the millennia. He is sometimes said to represent the triumph of light over darkness and of truth over error.
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- Tags: Guardian, Night Pharmacy
Hydroxyurea in the Treatment: Adverse Reactions
In: Disease
3 Jun 2010
In the study, the most commonly occurring adverse reactions were hema-tologic, including neutropenia, and low reticulocyte and platelet levels, which necessitated temporary cessation of therapy in almost all patients. Hemato-logic recovery usually occurred within two weeks. Other nonhematologic effects included skin rash, hair loss, fever, weight gain, gastrointestinal disturbances, bleeding, and parvovirus B-19 infection.
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Blog invites submissions of review articles, reports on clinical techniques, case reports, conference summaries, and articles of opinion pertinent to the control of pain and anxiety in dentistry.
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