Nonsteroidal Anti-inflanimatory Drug Use for Postoperative Dental Pain: RESEARCH-BASED

In: Dental treatment

8 Oct 2009

RESEARCH-BASED EVIDENCE IN POSTOPERATIVE DENTAL PAIN MODEL

A recent review paper by Swift states that NSAIDs (Ponstel canadian is a Nonsteroidal Anti-Inflammatory drug) are effective analgesics for postsurgical dental pain and that the adverse effects associated with NSAIDs are rarely seen when used for this purpose. Gastrointestinal toxicity, bleeding, renal toxicity, and potential of allergic reactions were identified as possible risks for the dental pain model. However, Swift did not use an evidence-based approach. An evidence-based approach will be used in this review in order to determine the strength of the information available to prove whether the above claims about NSAIDs are supported with actual evidence.

Table 1. Details of Randomized Controlled Trials in the Third Molar Surgical Model

Table 1. Details of Randomize

Table 1. Details of Randomize-2

Table 1. Details of Randomize-3

Table 1. Details of Randomize-4

Table 1. Details of Randomize-5

The evidence for analgesic efficacy and adverse effects of NSAIDs in the dental pain (Naprosyn canadian used to treat dental pain) model will be discussed in relation to the following: (a) choice of NSAIDs, (b) dosage of NSAIDs, (c) routes of administration ofTwenty-six third molar surgical randomized controlled trials (RCTs) with a total of 5742 analyzed patients published between 1986 and 2001 were selected. The inclusion criteria used were randomized allocation to treatment groups, which included the NSAIDs (Relafen tabletes it helps relieve pain and inflammation associated with rheumatoid arthritis and osteoarthritis) and placebo, and a standard outcome measure for pain to allow comparison of results. Analgesic efficacy and adverse effect outcomes were summarized and synthesized qualitatively in these 26 RCTs (Table 1). Of these 26 RCTs, 6 were general anesthesia (GA), 19 were local anesthesia (LA), and 1 was a conscious sedation model. These different types of studies are presented in a smaller summary table (Table 2). When scientific literature in a particular area of the dental surgical model was not available, evidence from other pain models was included when appropriate. Evidence was classified into 3 levels: RCTs (level I); case-control/epidemiologic studies (level II); and incomplete or inconsistent scientific literature (level III).

Table 2. Summary of Types of Studies

Percentage of

Patients

Number

Number

Reporting

Types of of

of

Minor Adverse

Studies Studies

Patients

Effects (M)

GA 6

1163

14.7

LA 19

4379

9

Conscious sedation 1

200

6

Total 26

5742


About this blog

Blog invites submissions of review articles, reports on clinical techniques, case reports, conference summaries, and articles of opinion pertinent to the control of pain and anxiety in dentistry.

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