Previous quantitative exercise BSPM studies in patients with CAD are scarce.’ One study of 100 patients suggested a positive correlation between the number of obstructed coronary arteries and both the severity of exercise ST depression at 80 ms after QRS offset and the anterior torso area over which it occurred. In another study of 27 patients the authors considered the size of the torso area of ST depression, 60 ms after the J point, in the ST difference map to be proportional to the severity of the underlying CAD. However, another study of 25 subjects reported no significant differences in the magnitude of ST integral minima or the spatial extent of ST integral decrease on the torso surface in patients with single-, as compared with multiple-, vessel CAD. Our findings are more in keeping with the former data. asthma inhalers
The ability of BSPM to spatially discriminate the primary artery involved in the ischemic process is not yet established. Eigenfunction analysis has been reported to effectively discriminate left anterior descending from right CAD. In contrast, the data of this study and one other study using isointegral analysis suggest that there is marked overlap of the patterns of exercise ST decrease on the body surface among the vessel subpopulations of patients with CAD.
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