In the present study, there were no significant changes found in any cardiorespiratory parameters after the initiation of PC-IRV at an I:E ratio of 2:1. In particular, Cl, Do2, and Vo2 remained unaltered by the use of PC-IRV These results demonstrate that the improvement in oxygenation which accompanies use of PC-IRV at this I:E ratio is not associated with any deleterious effects on cardiac function or tissue oxygen delivery. Because […]
In the present study, increases in Pa02 and decreases in PIP were found after the initiation of PC-IRV These results are similar to those found in previous investigations* of PC-IRV The changes found in PaC02 and pH were minimal and probably could have been eliminated had the end-expiratory pressure been decreased, as was made possible by the improvement in oxygenation accompanying the use of PC-IRV. Because PC-IRV has been demonstrated […]
Derived cardiorespiratory variables, systemic vascular resistance, pulmonary vascular resistance, arterial and mixed venous oxygen content, oxygen delivery, oxygen consumption, and oxygen extraction ratio were calculated using standard and previously described formulae. Where appropriate, cardiorespiratory and hemodynamic variables were normalized, […]
Nine patients (Table 1) with severe ARDS, as manifested by diffuse pulmonary infiltrates on chest roentgenograms, arterial hypoxemia with widened A-a gradients despite supplemental oxygen, pulmonary capillary wedge pressures (WP) less than 20 mm Hg, and decreased static and dynamic thoracic compliance were entered in the study. In each case, the patient was placed on PC-IRV at the request of the attending physician, who judged the patient to […]
Pressure controlled inverse ratio ventilation is a recently described-2 ventilatory modality, in which the conventional inspiratory to expiratory (I:E) ratio is reversed, with the inspiratory phase becoming two to four times as long as the expiratory period. The PC-IRV has been reported to achieve improved oxygenation at lower peak airway pressures. Other […]
The lack of significant correlation between PEEP and the IR, and the fact that in three patients, despite the change in PEEP (although small) and an unchanged EVLW, the IR remained within a 10% change, prove the independency of the IR in relation to the PEEP. Second, pleural effusion interfered with transthoracic impedance measurements of EVLW. Because the presence of EVLW by EIT is determined by the gas inflation differences, […]
Our data show that EIT, by using an IR that is based on ventilation-induced impedance changes in the anterior and the posterior parts of the lung, is a […]
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