Archive for the ‘Coronary Artery Disease’ Category

That is, on average, a patient who exercises to angina with three-vessel CAD is likely to have a greater amount of ischemic myocardium than a patient with two-vessel disease who also exercises to angina. Moreover, the same reasoning suggests that a larger sample population of normal subjects may have allowed a statistically significant difference in […]

One difference between the results of this study and those of our previous exercise BSPM study of 14 patients with isolated left anterior descending CAD was the generally higher correlation coefficients of peak ischemic ST changes and quantitative angiographic measures of myocardium at ischemic risk. In the previous study, the highest r value was —0.52 […]

Previous quantitative exercise BSPM studies in patients with CAD are scarce.’ One study of 100 patients suggested a positive correlation between the number of obstructed coronary arteries and both the severity of exercise ST depression at 80 ms after QRS offset and the anterior torso area over which it occurred. In another study of 27 […]

Certainly, the epidemiologic data from two recent studies of large patient populations have shown that the degree of exercise ST deviation, as measured from 12- and 15-lead electrocardiograms is a very strong and independent predictor of future coronary death and other clinical cardiac endpoints. A corollary of this reasoning is that CAD patients who fatigue […]

There were three major findings in this study. First, exercise BSPM provided quantitative discrimination among individual patients and patient groups with single- and multiple-vessel CAD. On average, patients with underlying multiple-vessel CAD and angina-limited exercise had significantly greater exercise ST integral decrease than patients with single-vessel CAD and angina. The CAD patients who fatigued during […]

Quantitative Coronary Angiography The modified Gensini scores of all CAD patients are displayed in Table 1. Groups 2 and 3 had similar mean scores (68 ± 30, group 2 vs 56 ± 18, group 3; NS); both were significantly (p<0.05) higher than those of group 4 and group 2 mean scores were also significantly (p<0.05) […]

As a discriminating variable, sum ST decrease ^ — 4,000 jjlV#s, cessation minus rest, appeared to provide the best criterion for prediction of single-vs multiple-vessel CAD in patients who achieved angina (Table 2). Retrospective application of this criterion to CAD groups 1 to 3 yielded a sensitivity of 85 percent, a specificity of 70 percent, […]

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