However, similar changes in skeletal muscle have been found with aging, disuse and malnutrition and may not be peculiar to patients with COPD. Whatever, the determinants of RM endurance are more complex than the determinants of RM strength. For the respiratory muscles, four factors could reduce the endurance time: low basal energy stores, low rate […]
In the endurance test of Nickerson and Keens, mean SIP/MIP percent was 68 ±3 percent. Our normal elderly subjects had a Ppk/MIP of 79 ±19 percent which was similar to the SIP max/MIP of 77 ± 6 percent found in normal younger subjects by Martyn et al. This suggests that learning occurs during the first […]
The MIP increased on subsequent visits in the normal elderly subjects, primarily from visit 1 to visit 2. Since the tests were spaced one week apart and only took 30 min to complete, there should not have been a training effect. Therefore, the increase in MIP suggests a learning effect. This was seen only in […]
This study showed that measures of inspiratory muscle strength and endurance (as measured by the 2-min incremental loading test) were significantly less in naive COPD patients than in the normal elderly subjects matched for age, height, weight and sex distribution. The MEP, max load, Pmean and Ppk/ MIP were reproducible on repeated testing in both […]
There was no difference between the normal elderly subjects and COPD patients in age, sex, height or weight (Table 1). The COPD patients had severe airflow limitation and markedly reduced MW (Table 1). The FEVi, FVC and MW were not different in either group from visit 1 to visit 3. The MIP was less in […]
The RM endurance was measured using a 2-min incremental threshold loading test. Section A of Figure 1 illustrates the weighted plunger and inspiratory port with an orifice of 6.6 cm2. Increased weights on the plunger required increased pressure to open the inspiratory port when the stopper was in place. Inspired minute ventilation and Vt were […]
In our laboratory, Martyn et al used a device similar to that of Nickerson and Keens but with the ability to add weights externally. Martyn et al started with low inspiratory loads which were increased at 2-min intervals so that subjects could develop strategies for managing progressively greater loads. This test was found to be […]
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