Archive for the ‘Cardiac Structure and Function’ Category

P-Wave Configuration as an Indicator of Echocardiographic Indices of Cardiac Structure and Function in Normotensive Adolescents: Discussion (Part 2)Systolic and diastolic BP tend to increase with age in […]

Their ECGs were normal by standard criteria, yet the P-waves were notched or biphasic in 22 subjects. These P-waves were morphologically and dimensionally normal, but when present, they predicted cardiac structural and functional differences among our normal adolescent subjects. Specifically, they were associated with higher measurements of systolic BP and LV mass than the subjects with unimodal P-waves, although these measurements were all within the conventionally defined normal range. Thus, […]

As shown in Table 2, subjects with a normal, yet bimodal, P-wave in lead V, had higher two-hour averaged systolic BP (108 ± 12 mm Hg vs 99 ±7 mm Hg, p<0.01, respectively) and conventional sphygmomanometer systolic BP (110 ±11 mm Hg vs 103 ±10 mm Hg, p = 0.05, respectively). Compared with the unimodal P-wave group, the bimodal P-wave group had greater LV mass (174 ±40 g vs 144 […]

P-Wave Configuration as an Indicator of Echocardiographic Indices of Cardiac Structure and Function in Normotensive Adolescents: Results (Part 1)By standard criteria, all subjects had normal P-waves in ECG lead V,. P-wave duration was normal (<110 ms) in […]

Echocardiography
M-mode and two-dimensional echocardiograms were recorded from standard views and measured according to the recommendations of the American Society of Echocardiography (ASE),H using a commercially available phased-array echocardiography (General Electric, Pass II, Milwaukee, WI).

Blood Pressure
Conventional BP was measured by one observer with a mercury sphygmomanometer with a cuff of appropriate size for the right arm of each subject after 15 minutes in a seated position. Phase V of the Korotkoff sounds was used to indicate diastolic pressure. The BP values represent the average of two determinations made two minutes apart. Automated BP was measured by the oseillometric method every eight minutes […]

Study Group
We attempted to enroll an entire seventh grade class of a local school district (Artesia Bellflower Cerritos) in this study. Forty-seven normotensive adolescents were available and were examined with two-dimensional and M-mode echocardiography, and BP measurements were obtained by two-hour automated BP monitoring. Seven subjects were excluded because the P-wave in ECG lead V, was either absent or of insufficient amplitude for analysis (see below). This left […]

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