Our study compared left anterior descending coronary artery flows and rates of coronary thrombolysis when systolic BP was pharmacologically increased with norepinephrine infusion or mechanically increased by inflation of a Fogarty catheter in the descending aorta. Systolic BP increased to a similar value with both interventions. Corresponding to the similar systolic BPs, diastolic BPs increased […]
Table 1 illustrates mean (±SE) values of hemodynamic effects of coronary thrombosis in all eight dogs. Note that following clot, systolic BP, pulmonary artery diastolic pressure, and heart rate remained constant and CO decreased (p<0.005). Female Pink Viagra Canadian Figure 2 depicts the effects of clot on blood flow in the left anterior descending coronary […]
Eight dogs (24 to 34 kg) were anesthetized with IV pentobarbital sodium (30 mg/kg) that was supplemented as required to maintain anesthesia. Their treatment conformed to the guidelines of the University of Manitoba Animal Care Committee. Each dog was mechanically ventilated in a right lateral decubitus position via an endotracheal tube with 100% 02 with […]
This study was designed to compare the effect of a mechanical vs a pharmacologic increase in BP on coronary artery blood flow and thrombolysis induced by IV administration of recombinant tissue plasminogen activator. We employed a canine model of coronary thrombosis induced by injection of radioactive blood clot in the left anterior descending coronary artery. […]
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