Archive for April, 2010

Heart Disease and Atrial Fibrillation: METHODS

In: Disease

22 Apr 2010

Study Population
We identified 143 patients with HF related to RHD and AF from our hospital’s cardiology ward between August 2000 and March 2002. Thirty-seven patients did not meet all of the inclusion criteria for enrollment, and 18 patients had clinical or echocardiographic data that caused them to be ineligible. Thus 88 patients were included in [...]

Heart Disease and Atrial Fibrillation

In: Disease

21 Apr 2010

INTRODUCTION
Traditionally, chronic heart failure (HF) has been attributed to a reduced systolic left ventricular (LV) function, accompanied by an increase in LV filling pressures and volumes (also called “systolic HF”). The important role of neuro-hormones in the pathophysiology of chronic HF is well recognized. Chronic HF is characterized by an increased activity of the neurohormonal [...]

Avoiding Opiate Toxicity with Patient-Controlled Analgesia by Proxy

In: Health

20 Apr 2010

Problem: After a 72-year-old woman underwent cancer surgery, her surgeon prescribed patient-controlled analgesia (PCA) with a 2-mg morphine loading dose and 1 mg every 10 minutes as needed, for a maximum of 6 mg/hour. Initially, the patient was restless and agitated in the post-anesthesia care unit, but she remained obtunded (not alert) after surgery. Despite [...]

VNSNY—Bringing the Caring Home

In: Main

19 Apr 2010

Imagine if you sat atop an organization whose mission for more than a century and a half was to boldly send nurses, home health aides, physicians, and others into every neighborhood, rich and poor, throughout the greater New York City area. Now you know what the Visiting Nurse Service of New York

FTC Report Partially Addresses PBMs and Medicare

In: Health

18 Apr 2010

Am n unpublicized report on pharmacy benefit managers (PBMs), issued this past August by the Federal Trade Commission (FTC), made me think of all those reports on the vulnerabilities of New Orleans that were ignored in advance of Hurricane Katrina in August/September. Mandated by Congress, the FTC report was supposed to determine whether PBMs, based [...]

Advances in Proton Pump Inhibitor Therapy: Reduction in Risk of Upper GI Bleeding in Critically Ill Patients

In: Main

17 Apr 2010

Conrad and colleagues established the efficacy of IR-OME in reducing the risk of 3 through 14 that had not cleared with 100 ml or more of lavage. Because this was a non-inferiority study, the primary efficacy analysis was conducted on the per-protocol population at the one-sided a = 0.025 level of significance.

Advances in Proton Pump Inhibitor Therapy: Elderly Populations

In: Main

16 Apr 2010

Older age produces a slight decrease in the elimination rate of omeprazole canadian and increases its bioavailability. Compared with a bioavailability of 58% in younger subjects, the bioavailability of a single 40-mg dose of IR-OME in healthy older subjects was 76%. The extent of metabolite excretion in the urine (70%) was similar to that observed in [...]

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